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MyMedichecks is your personal online dashboard where you can view your results, access clear and simple explanations about individual health markers, monitor changes in your health, and securely store information about your medical history, lifestyle and vital statistics.
FSH
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Oestradiol
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Oestradiol is the strongest of the three oestrogens. It's labelled a female hormone but it's made in both the ovaries and testes. It's responsible for the growth of breast tissue, the female reproductive system, and male sexual function.
In pre-menopausal women, oestradiol levels vary throughout the monthly cycle, peaking just before ovulation. Levels are lowest after menopause when the ovaries stop producing eggs. Low oestradiol levels in women can cause many symptoms associated with the menopause, including hot flushes, night sweats, and changes in mood. It can also increase the risk of osteoporosis (a condition where the bones become less dense).
In men, oestradiol levels tend to increase slightly with age as testosterone levels decline. Too much oestradiol in men can contribute to fertility problems, gynecomastia (enlarged breast tissue), and erectile dysfunction.
Progesterone
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Progesterone is a steroid hormone produced in the corpus luteum and the adrenal glands. Its main role is to prepare the body for and support a pregnancy. It is produced in increasing amounts in the second half of the menstrual cycle. Although progesterone is considered a female hormone, men also produce progesterone in the adrenal glands and the testes. Progesterone in men plays a role in testosterone production.
Prepare for your HRT Blood Test by following these instructions.
Sample collection and timing
Medications and supplements
Current guidance from the British Menopause Society and NICE recommends adjusting HRT primarily according to symptoms rather than blood hormone results.
Oestradiol levels vary depending on the type and dose of HRT, the timing of your last application or dose, and individual differences in absorption and metabolism. Therefore, levels do not always correlate with symptom control. A result within a typical range does not guarantee symptoms are well managed, and a lower result does not necessarily mean your HRT is not working.
If you take oral oestrogen (tablets), blood oestradiol is not a reliable measure of treatment response because much of the oestradiol is converted to oestrone before it reaches the bloodstream.
If you are perimenopausal, this test cannot distinguish between oestrogen produced naturally by your body and oestrogen from HRT.
Finger-prick samples may be affected by contamination if the sampling finger has come into contact with hormone gels, sprays or pessaries within the previous 4 weeks, even after washing.Despite these limitations, many people find this test useful. It can provide a baseline for monitoring over time, help identify possible absorption issues if HRT does not seem to be working as expected, or support discussions with a prescriber when symptoms persist despite higher-dose treatment. This test is not a substitute for clinical review, and we recommend discussing your results alongside your symptoms with your HRT prescriber before making any changes to your treatment.
Our test can be taken once you have reached menopause. If you have applied hormone gels, pessaries, or patches in the past four weeks, avoid taking your blood sample from the same finger you used to apply them. If you take biotin supplements, then we recommend that you don't take them for two days before this test. If you have been prescribed the supplements, discuss this with your doctor before you alter your dosage.
Broadly, HRT means the replacement of any deficient hormone. More commonly and in the case of our test, it refers to using oestrogen and progesterone to relieve menopausal symptoms such as hot flushes, lethargy, sleep disturbance, and vaginal dryness. Oestrogen hormones also help to prevent osteoporosis and atherosclerosis.
