Anti La SS - B Antibodies

Anti-La antibodies (also called SS-B antibodies) are autoantibodies that target specific proteins in cell nuclei. These antibodies are less common than Anti-Ro antibodies and rarely appear on their own - they're almost always found alongside Anti-Ro antibodies. Anti-La antibodies are particularly associated with Sjögren's syndrome, an autoimmune condition that primarily affects the glands that produce tears and saliva, causing dry eyes and dry mouth. When both Anti-Ro and Anti-La antibodies are present together, this combination is considered highly specific for Sjögren's syndrome. They can also be found in systemic lupus erythematosus (SLE) and other autoimmune conditions.