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Factor II Prothrombin mutation G20210A is a common genetic risk factor for thrombosis including deep venous thrombosis, DVT.
This mutation in the gene G20210A encoding the clotting factor prothrombin is found in about 1 in 50 persons in the UK.
A mutation in the gene G20210A raises the risk of thrombosis significantly for both males and females in all age groups.
Testing for prothrombin mutation G20210A is useful in determining a person's predisposition to thrombosis and can assist in determining the need for anticoagulant therapy.
People who have prothrombin mutation G20210A have a 2-to-3 fold increase in the risk of DVT.
Persons who have this mutation plus the Factor V Leiden mutation have a 10-to-20 fold increase in thrombotic risk.
Prothrombin mutations have also been linked with thrombotic events other than DVT, including recurrent miscarriage (repeat spontaneous abortions). In addition, there may be interactions with other risk factors for thrombosis, including pregnancy, the use of oral contraceptives, and immobilisation.
We send you an easy-to-use kit to collect your blood sample.
Post your sample to our lab in the prepaid envelope provided.
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Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.
We will send you your Factor II Prothrombin (gene G20210A) blood test sample collection kit together with the details of a convenient clinic where you can go and have your sample taken.
Your Factor II Prothrombin (gene G20210A) test includes 1st class postage and packaging for you to send your blood sample directly to our laboratory for analysis. If you live in an area where you cannot rely on the post or you simply want to ensure that your sample arrives at the laboratory the following day, you may wish to send your blood sample guaranteed next day delivery for extra reassurance.
Your blood sample will be analysed at one of our chosen laboratories. You can be assured of fast, accurate results from one of our accredited independent providers of clinical diagnostic tests.
Our medical team will comment on out-of-range blood test results and give you follow-up advice where necessary. If you need it, a PDF copy of your Factor II Prothrombin (gene G20210A) test results can be downloaded for your doctor.
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