A thyroid antibody test that is often used to investigate hyperthyroidism (Graves' disease) or to monitor the effectiveness of anti-thyroid treatment.
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Autoimmunity
TSH receptor antibodies
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TSH receptor antibodies cause Graves' disease hyperthyroidism. Graves disease is caused by the direct stimulation of the thyroid cells by TSH receptor stimulating antibodies. All forms of autoimmune thyrotoxicosis (Graves disease, Hashitoxicosis, neonatal thyrotoxicosis) are caused by the production of TSH receptor antibodies. These antibodies stimulate the thyroid gland independent of the normal regulated TSH stimulation.
Special instructions
How to prepare for your test
Prepare for your TSH Receptor Stimulating Antibodies Blood Test by following these instructions. Do not take biotin supplements for two days before this test, discuss this with your doctor if it is prescribed.
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FAQs
What are TSH receptor antibodies?
Thyroid-stimulating hormone (TSH) receptor antibodies can be classified as stimulating, blocking, or neutral. They are autoantibodies that attach to proteins in the thyroid and promote the production of thyroid hormones, leading to hyperthyroidism. Hyperthyroidism, or an overactive thyroid, occurs when the thyroid makes too much thyroxine (T4) and triiodothyronine (T3). An excess of thyroid hormones speeds up metabolism in the body. Hyperthyroidism symptoms include fatigue, unexplained weight loss, heart palpitations, sensitivity to heat and hair loss.
What can I learn from from a TSH receptor antibodies test?
Our test helps investigate symptoms of hyperthyroidism when an autoimmune condition is suspected as TSH receptor-stimulating antibodies are often associated with Graves' disease. You can also use it to monitor the progress and effectiveness of anti-thyroid therapy.
Why test thyroid antibodies?
Testing for thyroid antibodies helps distinguish an autoimmune thyroid disease from other thyroid conditions. Thyroid autoantibodies develop when the immune system mistakenly targets components of the thyroid gland or thyroid proteins, leading to chronic thyroid inflammation and disruption.