Immunoglobulins IgG IgM IgA Blood Test, from our experts to you.
Dr Sam Rodgers MBBS, MRCGP

Chief Medical Officer meet our doctors

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What are
antibodies?

Antibodies (also known as immunoglobulins) support the immune system, helping protect the body against non-self and harmful bacteria, viruses, and substances. There are five different classes of immunoglobulins and several subclasses. Each class represents a group of antibodies that has a slightly different role.


What can I learn
from this test?

Our test measures the amount of immunoglobulins A, G, and M (IgA, IgG, IgM) in your blood. This allows you to detect or monitor an excess or deficiency in one or more immunoglobulin classes.


What are
immunoglobulins A, G, and M?

Immunoglobulin M (IgM) antibodies are produced as a first response to a new non-self antigen, providing short-term protection. Then, immunoglobulin G (IgG) antibodies are produced during the initial infection. Around 70-80% of the immunoglobulins in the blood are IgG, and your body retains a catalogue of these antibodies to rapidly reproduce them whenever exposed to the same antigen. IgG antibodies form the basis of long-term protection against microorganisms. Immunoglobulin A (IgA) antibodies comprise about 15% of the total lung and stomach secretions and breast milk. IgA protects against infection in mucosal areas of the body, which are the soft tissue that lines your body's canals and organs in the digestive, respiratory, and reproductive systems.


What's included?

Immunity
Proteins
Select profile for more information

Immunoglobulin A Immunoglobulins or antibodies, play an important role in the immune system and help fight against harmful bacteria and viruses in the body. There are five classes of antibodies and several subclasses. Immunoglobulin A or IgA protects against infections of the membranes that line the mouth, airways, and digestive tract. IgA antibodies can also be found in saliva, tears, and breast milk.
Immunoglobulin G Immunoglobulins or antibodies, play an important role in the immune system and help fight against harmful bacteria and viruses in the body. There are five classes of antibodies and several subclasses. Around 70-80% of antibodies in the blood are Immunoglobulin G or IgG antibodies, capable entering the tissues and fighting infection. IgG provides the majority of antibody-based immunity. IgG antibodies form the basis of long-term protection against microorganisms and in those with a healthy immune system, sufficient IgG antibodies are produced to prevent re-infection.
Immunoglobulin M Immunoglobulins or antibodies, play an important role in the immune system and help fight against harmful bacteria and viruses in the body. There are five classes of antibodies and several subclasses. IgM antibodies are involved in the very early stages of an immune response and first to be made by the body when fighting a new infection, providing short-term protection.
Total Protein Total Protein represents the sum of the proteins albumin and globulin in your blood. Albumin and globulin have a range of functions including keeping blood within vessels, transporting nutrients and fighting infection. Abnormal levels can indicate malnutrition as well as a liver or kidney disorder.
Albumin Albumin is a protein which is made mainly in the liver. It helps to exert the osmotic pressure which holds water within the blood. It also helps carry nutrients and medications and other substances through the blood and is important for tissue growth and healing. Albumin also carries hormones around the body, therefore measuring the amount of albumin in the blood can help us calculate how much hormone is available to your tissues.
Globulin Globulin is an umbrella term for a set of different proteins that the immune system and the liver produce. Certain globulins bind with haemoglobin while others transport metals, such as iron, in the blood. Additionally, there is a certain type of globulin known as an immunoglobulin, (another name for an antibody) which helps to fight infection in the body.

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