Antinuclear Antibodies (ANA) Blood Test
    Antinuclear Antibodies (ANA) Blood Test
    Antinuclear Antibodies (ANA) Blood Test
    Antinuclear Antibodies (ANA) Blood Test

Antinuclear Antibodies (ANA) Blood Test

£99
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Check for the presence of ANA antibodies which are often raised in conditions like lupus, rheumatoid arthritis, and Sjögren's syndrome.

  • Results estimated in 4 working days
  • Convenient testing options
  • Bespoke doctor’s report
  • Free delivery

How do you want to take your sample?

  • Book a venous draw at a clinic   Venous
    +£35

    Visit one of our national clinic partners for a nurse to take your venous blood sample from a vein in your arm. We’ll email you instructions on how to book after we’ve processed your order.

  • Book a venous draw at home with a nurse Venous
    +£59

  • Self-arrange a professional sample collection Venous
    Free

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Is it for you?

Do you have symptoms of an autoimmune condition, or has someone in your family been diagnosed with one?

You may be experiencing lupus or Sjögren's syndrome symptoms, such as a facial rash, fatigue, swollen joints, hair loss, or dry eyes and mouth.

Our ANA blood test helps identify if you have lupus, rheumatoid arthritis, or Sjögren's syndrome by testing for antinuclear antibodies, which are often present in an autoimmune response. Antibody titre levels will only be provided if your result is positive.

Biomarker table

Autoimmunity

Antinuclear antibodies

Learn more
Antinuclear antibodies are produced by the immune system when it fails to distinguish between its own cells and foreign invaders such as bacteria and viruses. Antinuclear antibodies attack proteins inside the body's own healthy cells and cause symptoms such as inflammation, joint pain and fatigue.

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Dr Natasha Fernando

Medical Director

Dr Asia Ahmed

Digital Clinician

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FAQs

What can I learn from this test?
If are you experiencing symptoms, our test can help confirm if you have an autoimmune disease. However, a diagnosis is unlikely to be given from antibodies alone, as antibodies can be raised even if you have no evidence of disease. If your result is positive, you’ll also receive your ANA antibody titre levels.

What causes autoimmune conditions?

Autoimmune conditions happen if your immune system mistakes your body's cells as foreign cells and starts attacking them. Usually, your immune system is constantly looking for foreign bodies and will send out an army of fighter cells to attack them. However, if you have an autoimmune disease, your immune system mistakes parts of your body, like your joints or skin, as foreign. In this instance, it releases proteins called autoantibodies that attack healthy cells. Read more about this in our blog: Autoimmune disease – why one often follows another.

What is an ANA Blood Test?

Our Antinuclear Antibodies Blood Test sees whether you have auto-antibodies (which attack your cells) to help diagnose several autoimmune conditions, including lupus, rheumatoid arthritis, and Sjögren's syndrome.

Limitations of the test

Read before you order:

ANA has a very low specificity. This means our test could indicate you may have an autoimmune condition, even when you don’t (a false-positive result). Around three in 10 people will receive a false positive result. This can lead to unnecessary anxiety and further investigations. One reason for its low specificity is that ANA can be found in other conditions such as liver disease, inflammatory bowel conditions, and chronic infections. Certain drugs, like heart and blood pressure medications, may also increase ANA levels. 

Therefore, this test is most suitable when there’s a reasonable suspicion of a connective tissue disease and other more common causes of symptoms have been explored. Results are more clinically significant with ANA titres greater than 1:160. Titre levels will only be given if your result is positive.  

Although ANA is a good test for ruling out autoimmune disease, there’s a chance you could get a negative result when you do have an autoimmune disease (a false-negative result). False-negative results are less common and occur in about one in 20 cases. 

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