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Why take this test?
This advanced profile for endurance athletes covers all the bases, looking at markers which can help identify overtraining and injury as well as those that could cause lack of energy and motivation. Use this test to establish your pre-training baseline and then track changes as your training load increases.
This profile includes tests for inflammation and muscle damage, cholesterol for cardiovascular risk, hormones which can be affected by training such as testosterone, oestradiol and cortisol as well as markers for fatigue such as a full iron profile and vitamin B12.
All your results will be reviewed by a qualified doctor who can advise you on what changes you need to make to your training and nutrition.
We send you an easy-to-use kit to collect your blood sample.
Post your sample to our lab in the prepaid envelope provided.
View results securely in your own personal dashboard.
Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.
Haemoglobin carries oxygen and gives the red blood cell its red colour. This test measures the amount of haemoglobin in the blood and is a good measure of the blood's ability to carry oxygen around the body.
A high haemoglobin result can mean increased red cell production to compensate for chronically low oxygen levels in the blood caused by lung disease or living at altitude. While it can also indicate "blood doping" other causes can include dehydration, smoking and bone marrow disorders.
A low haemoglobin result indicates anaemia which can have many causes including pregnancy, blood loss, liver damage, iron deficiency and much more. A low haemoglobin level should be investigated in line with other symptoms and results.
HCT (haematocrit) measures the amount of space (volume) red blood cells take up in the blood.
Raised levels can result from pregnancy, living at altitude, dehydration as well as low availability of oxygen through chronic lung disease and even sleep apnoea.
Low levels indicate anaemia.
Red blood cell (RBC) count analyses the number of red cells in the blood. Red blood cells carry oxygen from the lungs to the rest of the body. They also carry carbon dioxide back to the lungs so that it can be exhaled.
A high count (thicker blood) means there is a chance that the red blood cells will clump together and block tiny blood vessels. This also makes it difficult for your red blood cells to carry oxygen.
A low count (anaemia) means that your body may not be getting the oxygen it needs and can be caused by nutritional deficiency (lack of iron, folic acid, vitamin B12), over-hydration as well as bleeding and bone marrow disorders.
MCV (mean corpuscular volume) reflects the size of your red blood cells.
A high result may indicate a vitamin deficiency of folate or vitamin B12 and is often seen in excessive alcohol consumption associated with liver inflammation.
A low result indicates anaemia, often caused by iron deficiency.
MCH (mean corpuscular haemoglobin) is the average amount of haemoglobin contained in your red blood cells.
Together with MCV and MCHC, MCH results can help in the diagnosis of different types of anaemia.
MCHC (mean corpuscular haemoglobin concentration) is the average concentration of haemoglobin in your red blood cells.
A high level can indicate the presence of spherocytes (a type of red bood cell with too much haemoglobin) or a deficiency of folic acid or vitamin B12 in the diet.
A low level can indicate chronic blood loss or iron deficiency.
RDW (red cell distribution width) shows whether the cells are all the same size or different sizes or shapes. Normally cells are fairly uniform, although a raised RDW result (indicating greater variation in cell size and shape than is normally seen) can be caused by deficiency in iron, vitamin B12 or folic acid.
White blood cells are key to your body's immune or defence system. They fight infections and protect your body from foreign invaders such as harmful germs and bacteria.
A raised white blood cell (WBC) count can indicate recent infection, inflammation, trauma and even stress. Your WBC can also be raised when taking certain medications.
A decreased WBC can result from a vitamin deficiency such as folate or vitamin B12, as well as liver disease and diseases of the immune system.
Neutrophils are a type of white blood cell that are responsible for helping your body fight infection. When neutrophils are low you can be more vulnerable to illness and infection.
Neutrophils can be raised after severe stress on the body from a bacterial infection, recent exercise or sudden kidney failure.
Low neutrophils can be caused by a deficiency in vitamin B12 or folic acid, severe bacterial infection and some autoimmune diseases.
Lymphocytes are a type of white blood cell which fight bacterial and viral infections. They include T cells, B cells and natural killer cells.
Lymphocytes can be elevated for many reasons but it is common for them to be raised after recent infection, particularly after the flu. They can also be raised due to autoimmune disorders and some cancers.
The most common cause for lymphocytes to be depleted is the common cold.
Monocytes are a type of white blood cell that engulf and remove pathogens and dead or damaged cells from our blood. The heat and swelling of inflammation is caused by the activities of these cells.
Elevated monocytes can indicate chronic inflammatory disease, chronic infection, parasitic infection and Cushings disease.
Low levels can be due to autoimmune disorders such as lupus and rheumatoid arthritis as well as drugs which affect the bone marrow such as those used in chemotherapy.
Eosinophils are a type of white blood cell whose function is to remove parasitic infections as well as to regulate inflammation to mark an infected site.
Levels of eosinophils can be elevated if the scale of inflammation is greater than necessary to control the damage (as is the case in asthma and allergic responses) as well as in parasitic and fungal infections, autoimmune diseases and skin disorders.
Low levels of eosinophils are not usually cause for concern and can be caused by the administration of steroids.
Basophils are a type of white blood cell that protect your body from bacteria and parasites such as ticks.
An elevated basophil count can be due to inflammatory conditions such as Crohn's disease, ulcerative colitis and dermatitis, recent infection and hormone imbalance (e.g. hypothyroidism).
A low basophil count can be caused by pregnancy, stress and use of steroids.
Platelets or clotting cells are the smallest type of blood cell and are important in blood clotting. When bleeding occurs, the platelets swell, clump together and form a sticky plug (a clot) which helps stop the bleeding.
If platelet levels are raised there is an increased risk of blood clots forming in blood vessels.
If platelet levels are too low there is a risk of easy bruising and uncontrolled bleeding.
MPV (mean platelet volume) is a measurement of the average size of your platelets. New platelets are larger than older ones and a raised MPV result occurs when increased numbers of platelets are being produced. MPV provides an indication of platelet production in your bone marrow.
Urea is waste product produced as the body digests protein and is carried by the blood to the kidneys, which filter the urea out of the blood and into the urine. The urea test examines how well the kidneys are functioning.
Raised levels of urea in the blood can be caused by dehydration or high protein consumption or may indicate that the kidneys are not working properly.
Low amounts of urea in the blood may indicate a low protein diet, excess hydration, malnutrition or liver failure.
Creatinine is a chemical waste molecule that is generated from muscle metabolism. Measurement of this is an indicator of the levels of other waste products in the body. Creatinine is an accurate marker of kidney function.
Elevated creatinine can be caused by high intake of animal protein, taking creatine supplements and vigorous exercise but can also indicate that the kidneys are not working properly.
Low creatinine can be caused by a low protein diet, reduced muscle mass or sometime that the kidneys are simply functioning efficiently.
The estimated glomerular filtration rate (eGFR) assesses how well the kidneys are working by estimating the amount of blood filtered through the kidneys. The glomeruli are tiny filters in the kidneys responsible for removing waste products. If these filters do not do their job properly, kidney function can be impaired. The eGFR calculation is an estimate of actual glomerular filtration rate, calculated using your age, weight, gender, and serum creatinine levels.
A normal or high eGFR indicates good kidney function.
A low eGFR result can indicate your kidneys are not working as well as they should. eGFR can be used to assess the severity of chronic kidney disease (CKD).
It is important to note that individuals with high muscle mass as well as people of certain ethnicities can have a low eGFR which is normal for them. If kidney damage is suspected then other investigative tests are recommended.
Alkaline phosphatase (ALP) is an enzyme found mainly in the liver and bones. Raised levels can indicate bone or liver disease. Elevated ALP is assessed in conjunction with other liver function tests to determine whether the problem lies in the liver or the bones.
Pregnancy can also cause raised ALP and it is often elevated in growing teenagers.
Alanine transferase (ALT) is an enzyme which is produced by the liver and can indicate liver damage caused by alcohol, drugs or viruses (hepatitis). Small amounts of ALT are normal, but raised levels may indicate that your liver is inflamed.
Elevated levels of ALT can also be caused by recent vigorous exercise.
CK (creatine kinase) is a muscle enzyme which signifies muscle cell damage and death. CK levels tend to be higher in people with greater muscle mass.
The level of CK in the blood is measured to assess muscle damage - it can rise rapidly after muscle trauma, but will subside as the damage repairs. If CK continues to rise it indicates that muscle damage is not being repaired. If you have been to the gym the day before your blood test you may well exhibit raised levels of CK.
Gamma GT is a liver enzyme which is raised in liver and bile duct diseases. It is used in conjunction with ALP to distinguish between bone or liver disease. Gamma GT is also used to diagnose alcohol abuse as it is raised in 75% of long term drinkers.
Bilirubin is a product of haemoglobin breakdown. It is removed from the body via the liver, stored and concentrated in the gall bladder and excreted into the bowel. Elevated levels can cause the skin and whites of eyes to become yellow (jaundice) as the liver is unable to remove enough bilirubin from the blood. This can indicate liver damage.
Bilirubin can also be raised due to a blocked bile duct as well as Gilbert's Syndrome.
Total Protein represents the sum of albumin and globulin. Abnormal levels can indicate malnutrition as well as a liver or kidney disorder.
Albumin is made mainly in the liver and helps to keep the blood from leaking out of blood vessels. It also helps carry some medicines and other substances through the blood and is important for tissue growth and healing.
Low albumin levels can indicate liver disease and can also be a marker for chronic ill-health, malnutrition and inflammation. It can also occur in kidney conditions such as nephrotic syndrome and diabetes.
Raised levels are usually caused by dehydration.
Globulin consists of different proteins and is made by the liver and the immune system. Certain globulins bind with haemoglobin while others transport metals, such as iron, in the blood and help fight infection.
HbA1c or Haemoglobin A1c is also known as glycosylated haemoglobin and is a longer term measure of glucose levels in your blood than a simple blood glucose test. Glucose attaches itself to the haemoglobin in your red blood cells, and as your cells live for around 8-12 weeks it provides a good indication of the level of sugar in your blood over a 2-3 month period.
This is an important measure for diagnosing type 2 diabetes as well as understanding how well blood sugar levels are being controlled in people who have already been diagnosed with diabetes.
This test measures how much iron is in your blood with the aim of identifying iron deficiency anaemia or iron overload syndrome (haemochromatosis)
The symptoms of too much or too little iron can be similar - fatigue, muscle weakness, moodiness and difficulty concentrating.
A raised result can mean that you have iron overload syndrome, an inherited condition where your body stores too much iron, or that you are over-supplementing or that you have a liver condition.
A low result can mean that you are anaemic or are suffering from gastro-intestinal blood loss (or other blood loss). Anaemia is also very common in pregnant women.
Total iron binding capacity (TIBC) is a measure of the amount of iron that can be carried through the blood.
A raised TIBC result usually indicates iron deficiency whereas low TIBC can occur with iron overload syndrome (haemochromatosis).
Transferrin is made in the liver and is the major protein in the blood which binds to iron and transports it through the body.
Low transferrin saturation levels can indicate iron deficiency while high levels can indicate iron overload.
Ferritin is a protein which stores iron in your cells for your body to use later. Measuring ferritin levels gives us a good indication of the amount of iron stored in your body.
Low levels of ferritin can indicate anaemia which can be caused by excessive or chronic bleeding, poor absorption of iron or too little iron in the diet.
Raised ferritin levels can indicate iron overload syndrome (haemochromatosis) or any kind of liver damage. It is also a marker of infection and inflammation.
Triglycerides are a type of fat (lipid) that circulate in the blood. After you eat, the body converts excess calories into triglycerides which are then transported to cells to be stored as fat. Your body releases triglycerides to be used for energy.
Raised triglycerides are thought to be a risk factor for peripheral vascular disease (affecting the blood vessels which supply your arms and legs as well as organs below the stomach) as well as microvascular disease, affecting the tiny blood vessels around the heart.
Cholesterol is an essential body fat (lipid). It is necessary for building cell membranes and for producing a number of essential hormones. Cholesterol is manufactured in the liver and also comes from the food we eat. Elevated cholesterol is a risk factor for heart disease - the recommended level is below 5 mmol/L.
Cholesterol however is made up of both good (HDL) and bad (LDL) cholesterol so it is important to investigate a raised total cholesterol result to determine the cause. High levels of HDL cholesterol can cause a raised total cholesterol result but may actually be protective against heart disease.
HDL cholesterol (high density lipoprotein) removes cholesterol from the bloodstream and transports it to the liver where it is broken down and removed from the body in bile. HDL cholesterol is commonly known as "good cholesterol".
Raised levels are believed to be protective against heart disease, while low levels are associated with increased risk of a heart attack.
LDL cholesterol (low density lipoprotein) carries cholesterol, triglycerides and other fats to various tissues throughout the body. Too much LDL cholesterol, commonly called "bad cholesterol", can cause fatty deposits to accumulate on artery walls, potentially leading to atherosclerosis and heart disease.
Non-HDL cholesterol is calculated by subtracting your HDL cholesterol result from your total cholesterol. It therefore includes all the non-protective and potentially harmful cholesterol in your blood, not just the LDL cholesterol. As such, it is considered to be a better marker for cardiovascular risk than total cholesterol and LDL cholesterol. The recommended level of non-HDL cholesterol is below 4 mmol/L.
HDL % of total cholesterol is considered to be more indicative of your risk of cardiovascular disease than total cholesterol alone.
A result below 20% indicates an increased risk of cardiovascular disease, while one above 20% indicates a lower than average risk.
C-Reactive Protein (CRP) is an inflammation marker used to assess whether there is inflammation in the body - it does not identify where the inflammation is located. High Sensitivity CRP (CRP-hs) is a test which is used to detect low-level inflammation which is thought to damage blood vessels which can lead to a heart attack or stroke.
Raised levels are a risk factor for cardio-vascular disease.
Thyroid Stimulating Hormone (TSH) is produced in the pituitary gland and stimulates the thyroid gland to produce thyroid hormones thyroxine (T4) and triiodothyronine (T3).
High levels of TSH indicate an underactive thyroid while low levels indicate an overactive thyroid. In primary pituitary failure, a low TSH will be associated with an underactive thyroid.
Thyroxine (T4) is one of two hormones produced by the thyroid gland. Most T4 is bound to carrier proteins in the blood. This test measures the level of T4 which is free, or unbound, circulating in your blood.
High levels of free thyroxine can indicate an overactive thyroid while low levels can indicate an underactive thyroid.
Testosterone is a male sex hormone which is produced in the testicles of men and, in much smaller amounts, in the ovaries of women. It is responsible for bone and muscle strength, as well as mood, energy and sexual function.
Testosterone levels decline with age and it is unusual to find naturally elevated levels in men. Low testosterone is more common than raised testosterone in the absence of supplementation.
In women, raised testosterone can result in male characteristics such as body hair, greater bulk, a deeper voice and acne - all symptoms of polycystic ovaries, a condition in which elevated testosterone is commonly seen.
Cortisol is a stress hormone produced by the adrenal glands. It is vital to survival given its role in functions such as immunity, regulating blood pressure and releasing insulin for blood sugar maintenance.
Raised cortisol levels (Cushing's syndrome) can lead to rapid weight gain, especially around the waist, excessive body hair (in women) and loss of libido and erectile dysfunction (in men).
Low levels of cortisol (Addison's disease) can lead to fatigue, nausea, skin discolouration and low blood pressure.
The Testosterone/Cortisol (T:C) ratio is good measure of whether athletes are recovering well after intense training. Testosterone is an anabolic hormone which helps to build muscle, produce red blood cells and increase aerobic metabolism in muscles. Cortisol is a catabolic hormone working antagonistically with testosterone, inhibiting protein synthesis and blocking anabolic signalling. The T:C ratio is more sensitive to the stresses of training than either measure alone. Over time it can be trended to see how well you are recovering.
Chronically elevated cortisol levels in the body, breaks down muscle and weakens the immune system. For both endurance and strength training athletes, the T:C ratio provides a useful marker of possible over-reaching and over-training syndromes, which is where the body does not sufficiently recover after exercise. Poor recovery can lead to a decline in performance, physiological stress and low mood.
A 30% decrease in T:C ratio has been suggested as an indicator for insufficient recovery and can point towards overtraining. If this is the case it is extremely important to reflect on your training routine and make sure you recover sufficiently to prevent long-term ill-health.
DHEAS is the sulphated form of DHEA, a hormone which is produced by the adrenal glands and is responsible for male characteristics in both men and women. DHEAS gradually declines from the age of 30 onwards.
A raised result in women may contribute to hirsuitism (excess hair) as well as male body characteristics. It can also be raised in polycystic ovary syndrome.
In both sexes raised DHEAS may indicate Cushing's disease (when the body produces too much cortisol) as well as a possible adrenal tumour.
Low levels of DHEAS may indicate adrenal dysfunction and could contribute to a low libido, fertility problems and, in women, osteoporosis.
Raised levels are often seen in individuals who supplement with DHEA.
Oestradiol is a female steroid hormone which is produced in the ovaries of women and to a much lesser extent in the testes of men. It is responsible for the female reproductive system as well as the growth of breast tissue and bone thickness. Oestradiol levels decline with age, culminating in the menopause when the ovaries stop producing eggs.
Raised oestradiol in women can cause acne, constipation, loss of sex drive and depression as well as raising the risk of uterine and breast cancer.
Oestradiol can also be raised in men due to excess fat (which produces oestradiol) or in relation to testosterone levels which have declined with age. Raised oestradiol in men can cause the growth of breast tissue, the loss of libido and infertility.
Low levels of oestradiol in women can lead to osteoporosis, problems with the menstrual cycle and fertility as well as fatigue and depression.
Magnesium is an important mineral needed for proper muscle, nerve, and enzyme function. It helps the body make and use energy and aids the movement of electrolytes such as potassium and sodium into and out of cells.
The kidneys remove any excess magnesium from the body so developing raised magnesium levels (hypermagnesemia) is rare. However, those with kidney problems and those supplementing high amounts of magnesium may be at risk of developing hypermagnesemia.
A low magnesium level can be caused by poor nutrition and a high intake of alcohol. Magnesium is found in a variety of foods including nuts, leafy green vegetables, legumes and whole grains.
Zinc is necessary for immune function, wound healing, taste, smell and is essential for cell division and growth. Zinc also removes toxic metals such as copper, lead and mercury from the brain.
Even though zinc is an essential requirement for a healthy body, too much zinc can be harmful. Care is needed when taking zinc supplements as it is possible to overdose on zinc. A raised zinc result may be due to over supplementing.
A low result may be caused by a lack of zinc in your diet. Zinc can be found in red meat, poultry, pulses, seeds and nuts.
Vitamin B12 is important for production of red blood cells which carry oxygen around the body - low levels can cause anaemia with associated symptoms of lack of energy and fatigue. It is also important in metabolism and for the nervous system and prolonged lack of vitamin B12 may cause nerve damage. Vitamin B12 is almost entirely found in meat and animal food products.
Around 70% of vitamin B12 is bound to carrier proteins in your blood. This test measures the level of unbound or active B12 which is available for your cells.
Raised levels of vitamin B12 can indicate a blood or liver disorder.
Low levels are seen in people with pernicious anaemia, an autoimmune disease which prevents the absorption of vitamin B12, or those with restrictive diets such as vegans.
Folate is a water soluble vitamin which is needed by the body in your diet every day. It plays a role in DNA replication and protection, it's important for the production of red blood cells as well as in the prevention of neural tube defects in babies.
Low levels can indicate anaemia and can be implicated in raised homocysteine levels.
Although called a vitamin, vitamin D is actually a hormone which is activated by sunshine on your skin. Vitamin D is essential for bone strength as it helps your intestines absorb calcium. However, it is thought that vitamin D also plays an important role in immune function, as well as in many chronic diseases and mental health.
Many people in the UK do not produce enough Vitamin D, especially in the winter months with fewer daylight hours. It is now recommended that you get 10 - 15 minutes of unprotected sun exposure every day to ensure you are producing enough vitamin D. In winter months, if your levels are found to be low, you may wish to take a supplement.
We will send you your Endurance Fit blood test sample collection kit together with the details of a convenient clinic where you can go and have your sample taken.
Your Endurance Fit test includes 1st class postage and packaging for you to send your blood sample directly to our laboratory for analysis. If you live in an area where you cannot rely on the post or you simply want to ensure that your sample arrives at the laboratory the following day, you may wish to send your blood sample guaranteed next day delivery for extra reassurance.
Your blood sample will be analysed at one of our chosen laboratories. You can be assured of fast, accurate results from one of our accredited independent providers of clinical diagnostic tests.
Our medical team will comment on out-of-range blood test results and give you follow-up advice where necessary. If you need it, a PDF copy of your Endurance Fit test results can be downloaded for your doctor.
Once you have placed your order you will receive login details to mymedichecks.com where you can manage your account, track your orders and view your Endurance Fit test results.
Stay motivated by filling in your online health and lifestyle questionnaire and seeing how improvements in your lifestyle can influence your test results. Your medical and family history gives us vital information when interpreting your results.