Hashimoto's thyroiditis or Hashimoto's disease is an autoimmune disease where the body's immune system attacks cells of the thyroid gland, resulting in lower production of thyroid hormones. Hashimoto's disease is named after Hakaru Hashimoto who first described it in 1912.
Histamine is a chemical that is frequently involved in allergic reactions and is released by specialised blood cells called basophils and mast cells. Histamine causes swelling of the local tissues (which if in the nose or throat can cause blocked nose and difficulty breathing), increased blood flow into that area causing redness and the release of other substances such as kinins that cause itching.
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