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Why take this test?
Our Liver Check (also known as a Liver Function Test) is a comprehensive examination of liver enzymes such as gamma GT (GGT) and alanine transferase (ALT) which can be elevated if the liver is inflamed or if the biliary system is obstructed.
The main causes of liver disease are excessive alcohol or calorie consumption and viruses such as hepatitis. Fatty liver disease is also on the rise due to increasingly unhealthy lifestyles. Our Liver Check can help you to determine if your lifestyle is damaging your liver. If caught early, liver inflammation can be reversed before it causes irreparable damage.
Our Liver Check blood test also includes tests for kidney function, iron, gout and cholesterol.
This easy at-home finger-prick blood test will give you all the information you need to know whether you need to moderate your lifestyle. With a doctor's comments included with every test, we'll tell you what your results mean and what you need to do next.
As well as for people monitoring an existing liver condition, the Liver Check is designed for those who want to find out if their lifestyle is damaging their liver - particularly if they are worried about excessive alcohol, calorie or drug consumption. Early detection of liver damage means that preventative action can be taken before deterioration becomes irreversible.
We send you an easy-to-use kit to collect your blood sample.
Post your sample to our lab in the prepaid envelope provided.
View results securely in your own personal dashboard.
Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.
Bilirubin is a product of haemoglobin breakdown. It is removed from the body via the liver, stored and concentrated in the gall bladder and excreted into the bowel. Elevated levels can cause the skin and whites of eyes to become yellow (jaundice) as the liver is unable to remove enough bilirubin from the blood. This can indicate liver damage.
Bilirubin can also be raised due to a blocked bile duct as well as Gilbert's Syndrome.
Alkaline phosphatase (ALP) is an enzyme found mainly in the liver and bones. Raised levels can indicate bone or liver disease. Elevated ALP is assessed in conjunction with other liver function tests to determine whether the problem lies in the liver or the bones.
Pregnancy can also cause raised ALP and it is often elevated in growing teenagers.
Alanine transferase (ALT) is an enzyme which is produced by the liver and can indicate liver damage caused by alcohol, drugs or viruses (hepatitis). Small amounts of ALT are normal, but raised levels may indicate that your liver is inflamed.
Elevated levels of ALT can also be caused by recent vigorous exercise.
CK (creatine kinase) is a muscle enzyme which signifies muscle cell damage and death. CK levels tend to be higher in people with greater muscle mass.
The level of CK in the blood is measured to assess muscle damage - it can rise rapidly after muscle trauma, but will subside as the damage repairs. If CK continues to rise it indicates that muscle damage is not being repaired. If you have been to the gym the day before your blood test you may well exhibit raised levels of CK.
Gamma GT is a liver enzyme which is raised in liver and bile duct diseases. It is used in conjunction with ALP to distinguish between bone or liver disease. Gamma GT is also used to diagnose alcohol abuse as it is raised in 75% of long term drinkers.
Urea is waste product produced as the body digests protein and is carried by the blood to the kidneys, which filter the urea out of the blood and into the urine. The urea test examines how well the kidneys are functioning.
Raised levels of urea in the blood can be caused by dehydration or high protein consumption or may indicate that the kidneys are not working properly.
Low amounts of urea in the blood may indicate a low protein diet, excess hydration, malnutrition or liver failure.
Creatinine is a chemical waste molecule that is generated from muscle metabolism. Measurement of this is an indicator of the levels of other waste products in the body. Creatinine is an accurate marker of kidney function.
Elevated creatinine can be caused by high intake of animal protein, taking creatine supplements and vigorous exercise but can also indicate that the kidneys are not working properly.
Low creatinine can be caused by a low protein diet, reduced muscle mass or sometime that the kidneys are simply functioning efficiently.
The estimated glomerular filtration rate (eGFR) assesses how well the kidneys are working by estimating the amount of blood filtered through the kidneys. The glomeruli are tiny filters in the kidneys responsible for removing waste products. If these filters do not do their job properly, kidney function can be impaired. The eGFR calculation is an estimate of actual glomerular filtration rate, calculated using your age, weight, gender, and serum creatinine levels.
A normal or high eGFR indicates good kidney function.
A low eGFR result can indicate your kidneys are not working as well as they should. eGFR can be used to assess the severity of chronic kidney disease (CKD).
It is important to note that individuals with high muscle mass as well as people of certain ethnicities can have a low eGFR which is normal for them. If kidney damage is suspected then other investigative tests are recommended.
Total Protein represents the sum of albumin and globulin. Abnormal levels can indicate malnutrition as well as a liver or kidney disorder.
Albumin is made mainly in the liver and helps to keep the blood from leaking out of blood vessels. It also helps carry some medicines and other substances through the blood and is important for tissue growth and healing.
Low albumin levels can indicate liver disease and can also be a marker for chronic ill-health, malnutrition and inflammation. It can also occur in kidney conditions such as nephrotic syndrome and diabetes.
Raised levels are usually caused by dehydration.
Globulin consists of different proteins and is made by the liver and the immune system. Certain globulins bind with haemoglobin while others transport metals, such as iron, in the blood and help fight infection.
Uric acid is a waste product from the digestion of protein. High levels can lead to excess uric acid being deposited as crystals in the tissues of the body. When this occurs in joints it causes the painful condition known as gout.
Uric acid levels are best tested 6 weeks after symptoms appear as they may not be raised at the onset of a gout attack.
This test measures how much iron is in your blood with the aim of identifying iron deficiency anaemia or iron overload syndrome (haemochromatosis)
The symptoms of too much or too little iron can be similar - fatigue, muscle weakness, moodiness and difficulty concentrating.
A raised result can mean that you have iron overload syndrome, an inherited condition where your body stores too much iron, or that you are over-supplementing or that you have a liver condition.
A low result can mean that you are anaemic or are suffering from gastro-intestinal blood loss (or other blood loss). Anaemia is also very common in pregnant women.
Total iron binding capacity (TIBC) is a measure of the amount of iron that can be carried through the blood.
A raised TIBC result usually indicates iron deficiency whereas low TIBC can occur with iron overload syndrome (haemochromatosis).
Transferrin is made in the liver and is the major protein in the blood which binds to iron and transports it through the body.
Low transferrin saturation levels can indicate iron deficiency while high levels can indicate iron overload.
Triglycerides are a type of fat (lipid) that circulate in the blood. After you eat, the body converts excess calories into triglycerides which are then transported to cells to be stored as fat. Your body releases triglycerides to be used for energy.
Raised triglycerides are thought to be a risk factor for peripheral vascular disease (affecting the blood vessels which supply your arms and legs as well as organs below the stomach) as well as microvascular disease, affecting the tiny blood vessels around the heart.
Cholesterol is an essential body fat (lipid). It is necessary for building cell membranes and for producing a number of essential hormones. Cholesterol is manufactured in the liver and also comes from the food we eat. Elevated cholesterol is a risk factor for heart disease - the recommended level is below 5 mmol/L.
Cholesterol however is made up of both good (HDL) and bad (LDL) cholesterol so it is important to investigate a raised total cholesterol result to determine the cause. High levels of HDL cholesterol can cause a raised total cholesterol result but may actually be protective against heart disease.
HDL cholesterol (high density lipoprotein) removes cholesterol from the bloodstream and transports it to the liver where it is broken down and removed from the body in bile. HDL cholesterol is commonly known as "good cholesterol".
Raised levels are believed to be protective against heart disease, while low levels are associated with increased risk of a heart attack.
LDL cholesterol (low density lipoprotein) carries cholesterol, triglycerides and other fats to various tissues throughout the body. Too much LDL cholesterol, commonly called "bad cholesterol", can cause fatty deposits to accumulate on artery walls, potentially leading to atherosclerosis and heart disease.
Non-HDL cholesterol is calculated by subtracting your HDL cholesterol result from your total cholesterol. It therefore includes all the non-protective and potentially harmful cholesterol in your blood, not just the LDL cholesterol. As such, it is considered to be a better marker for cardiovascular risk than total cholesterol and LDL cholesterol. The recommended level of non-HDL cholesterol is below 4 mmol/L.
HDL % of total cholesterol is considered to be more indicative of your risk of cardiovascular disease than total cholesterol alone.
A result below 20% indicates an increased risk of cardiovascular disease, while one above 20% indicates a lower than average risk.
We will send you your Liver Check finger-prick blood sample collection kit which contains everything you need to take your blood sample in the comfort of your own home. If you are unsure about completing a finger-prick blood sample collection you will have the opportunity to select a clinic-based venous blood sample option during the checkout process.How to collect a finger-prick blood sample
Your Liver Check includes 1st class postage and packaging for you to send your blood sample directly to our laboratory for analysis. If you live in an area where you cannot rely on the post or you simply want to ensure that your sample arrives at the laboratory the following day, you may wish to send your blood sample guaranteed next day delivery for extra reassurance.
Your blood sample will be analysed at one of our chosen laboratories. You can be assured of fast, accurate results from one of our accredited independent providers of clinical diagnostic tests.
Our medical team will comment on out-of-range blood results and give you follow-up advice where necessary. If you need it, a PDF copy of your Liver Check results can be downloaded for your doctor.
Once you have placed your order you will receive login details to mymedichecks.com where you can manage your account, track your orders and view your Liver Check results.
Stay motivated by filling in your online health and lifestyle questionnaire and seeing how improvements in your lifestyle can influence your results. Your medical and family history gives us vital information when interpreting your results.