C1 esterase inhibitor is a protein which is produced mainly in the liver and is found in the fluid part of your blood.
C1 esterase inhibitor controls C1, which is the first component of the complement system.
The complement system is a group of proteins that work with the immune system and play a role in the development of inflammation.
This test is useful where a person has signs of hereditary angioedema (C1 esterase inhibitor deficiency).
C1 esterase inhibitor deficiency causes swelling of face and throat. Gut swelling may cause severe abdominal pain, which may be mistaken for acute abdominal conditions such as appendicitis. Dermal swellings are deeper and larger than urticaria ('nettle rash'). They may be painful and are not itchy.
Onset of symptoms is usually in adolescence but may occur at any age. Occasionally C1 esterase inhibitor deficiency is asymptomatic.
We will send you your C1 Esterase Inhibitor blood and test sample collection kit together with the details of a convenient clinic where you can go and have your sample taken.
Your C1 Esterase Inhibitor test includes 1st class postage and packaging for you to send your blood and sample directly to our laboratory for analysis. If you live in an area where you cannot rely on the post or you simply want to ensure that your sample arrives at the laboratory the following day, you may wish to send your blood and sample guaranteed next day delivery for extra reassurance.