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Gluten Sensitivity, Gluten Intolerance, can cause an inflammatory disease called Coeliac (celiac) disease.
Coeliac disease is a life-long inflammatory disease of the upper small intestine caused by intolerance to the gluten affecting many genetically susceptible individuals.
Gluten is a protein found in wheat, and other similar proteins found in rye, barley and oats.
These proteins damage the small finger-like projections (villi) that line the small intestine. When damaged and inflamed, the villi are unable to absorb water and nutrients such as vitamins, folic acid, iron and calcium. This causes the coeliac to be susceptible to a variety of other conditions related to malabsorption, including lactose intolerance.
Apart from the inability to absorb nutrients, damaged lining to the small intestine has other negative results. It is unable to produce sufficient digestive enzymes essential to break down foods for complete digestion and absorption, such as lactose and carbohydrates. Large components of foods remain in the digestive tracts unabsorbed which are in turn fermented by bacteria living naturally in our digestive tract and ideal conditions causing cramps, gas, bloating, flatulence and diarrhoea.
Coeliac disease has many and varied symptoms, and adult symptoms are different from those of children. A range of symptoms and signs may be associated with untreated coeliac disease. Diarrhoea is one of the most common symptoms to affect people of all ages with coeliac disease. Children may not gain weight or grow properly, while adults may find they lose weight. Malabsorption may also leave people tired and weak, because of anaemia caused by iron or folate deficiency.
Gluten Intolerance can go misdiagnosed because persons going for coeliac blood tests present themselves on a gluten free diet, hence antibodies are not present in their blood and tests prove false negative.
Coeliac disease is sometimes associated with other conditions including type 1 (insulin-dependent) diabetes, autoimmune thyroid disease and ulcerative colitis.
We send you an easy-to-use kit to collect your blood sample.
Post your sample to our lab in the prepaid envelope provided.
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Our tests are not a substitute for seeing your doctor, especially if you are suffering symptoms. Our doctors will interpret your results based on the information you have provided, but will not diagnose, consult or provide any treatment. You will be advised to see your doctor for any necessary follow-up action.
Tissue Transglutaminase (tTG) IgA is an autoantibody produced in the immune response seen in Coeliac disease.
Coeliac disease is an autoimmune condition caused by a sensitivity to gluten. It can start at any age, but most people are diagnosed in adulthood. Once you have coeliac disease you will have it for life. Exposure to gluten causes inflammation in the lining of the small intestine causing pain and irritation, preventing food and nutrients from being digested effectively.
A negative result does not necessarily exclude Coeliac disease. If you are symptomatic you may require further testing.
We will send you your Gluten Sensitivity Evaluation blood test sample collection kit together with the details of a convenient clinic where you can go and have your sample taken.
Your Gluten Sensitivity Evaluation test includes 1st class postage and packaging for you to send your blood sample directly to our laboratory for analysis. If you live in an area where you cannot rely on the post or you simply want to ensure that your sample arrives at the laboratory the following day, you may wish to send your blood sample guaranteed next day delivery for extra reassurance.
Your blood sample will be analysed at one of our chosen laboratories. You can be assured of fast, accurate results from one of our accredited independent providers of clinical diagnostic tests.
Our medical team will comment on out-of-range blood test results and give you follow-up advice where necessary. If you need it, a PDF copy of your Gluten Sensitivity Evaluation test results can be downloaded for your doctor.
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